evaluate the efficacy and safety profile of Rosuvastatin, Simvastatin and Atorvastatin in newly diagnosed type 2 diabetic patients with dyslipidaemia
نویسندگان
چکیده
Dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. The lipid changes associated with mellitus are attributed to increased free fatty acid flux secondary insulin resistance. This prospective, comparative, open label, randomized and parallel group. subjects enrolled this study were selected from Out-Patient Department Medicine collaboration Pharmacology, Tertiary care teaching hospital over a period month. Newly diagnosed 90 cases patients Type II Diabetes Mellitus well controlled on oral hypoglycemic drugs randomly divided into 3 groups 30 each. Group A was received Rosuvastain 10 mg O.D months, B: Simvastatin C Atrovastatin O.D. In ‘A’ mean difference Total Cholesterol between baseline versus after 6 months 82.37 mg/dl, 64.92 mg/dl 52.23 B respectively. Triglycerides 65.04 A, 39.99 37.04 C.
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The ever increasing interventional CVD outcome studies have resulted in statins being an essential factor of cardiovascular prevention strategies. The JUPITER study in 2008, despite reducing CVD and overall mortality, highlighted an increase in new onset diabetes in the rosuvastatin treated arm. Since then there have been many meta-analyses of the RCTs and the largest carried out by Sattar et a...
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Objectives. To investigate the efficacy and the safety of the three most commonly prescribed statins (rosuvastatin, atorvastatin, and pravastatin) for managing dyslipidemia among diabetic patients in Qatar. Subjects and Methods. This retrospective observational population-based study included 350 consecutive diabetes patients who were diagnosed with dyslipidemia and prescribed any of the indica...
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ژورنال
عنوان ژورنال: International Journal of Health Sciences (IJHS)
سال: 2022
ISSN: ['2550-6978', '2550-696X']
DOI: https://doi.org/10.53730/ijhs.v6ns4.10009